For more than 25 years Antec has been the world’s leading supplier of analyzers using High Performance Liquid Chromatography (HPLC) with Electrochemical Detection (EC). Validated applications for environmental, food, clinical and pharmaceutical analysis have been successfully developed using the ALEXYS LC-EC systems. With its ultra-sensitive Electrochemical Detectors Antec has become the key supplier for neurotransmitter analysis.
Antec ALEXYS Analyzers
UHPLC with electrochemical detection
- Optimised in every detail
- Designed for performance
- Parallel analysis with multiple flow cells
- Micro volume sample handling
The ALEXYS™ is a HPLC system with electrochemical detection that has been designed to meet the highest demands for detection sensitivity and performance. The ALEXYS is easily upgradeable to micro-bore and capillary LC-EC. The system uses Clarity, a fully featured data acquisition software with all the tools for automated data acquisition, calibration, processing and reporting.
An ALEXYS analyzer additionally has the appropriate kit that is optimized for a specific application. For example, guaranteed applications have been developed for the analysis of neurotransmitters such as noradrenaline, dopamine, serotonin and metabolites in microdialysates. Typically, picomolar concentration detection limits have been obtained in only a few microliters of sample. Parallel detection schemes using multiple flow cells have been developed for time, sample and experimental cost savings! The ALEXYS has proven its performance in routine analysis in clinical, food & beverage, environmental and pharmaceutical laboratories as well. For more information download a brochure,
Antec is known for its electrochemical detectors (ECD), providing unprecedented sensitivity in HPLC analyses. In almost any kind of application in conventional HPLC, UHPLC, Micro-, Capillary- and Nano HPLC, ECD is extremely selective and sensitive. It is applied routinely in a number of analyses such as neurotransmitters, (poly)phenols, carbohydrates, and a large variety of pharmaceutical compounds.
The DECADE Elite detector with its advanced electronics provides an enormous linear dynamic range of more than 6 orders of magnitude. The DECADE Elite is used in Antec’s ALEXYS systems, or with any other commercial HPLC or UHPLC system such as Waters, Agilent, Thermo-Fisher, Shimadzu, Jasco, Perkin Elmer, and Knauer.
Flow cells for detection
The SenCell is a new generation electrochemical flow cell specially designed for highest sensitivity. The VT03 is its predecessor, for many years one of a kind and unsurpassed in detection sensitivity. The Flexcell with its replaceable working electrode is specifically developed for electrode consuming applications.
Clarity software for system control and data acquisition
- Fully featured data acquisition software
- Up to 4 independent timebases
- Multiple instrument control
- GLP, 21 CFR part 11 compliance
Clarity from DataApex is an advanced modular software package for data acquisition, data processing and instrument control. Up to four independent LC systems each with up to 12 detectors can be simultaneously connected. Optional ‘Control modules’ provide integrated control of selected instruments, ‘Extensions’ provide specialized functionality for PDA or GPC analysis. Its wide range of data acquisition interfaces (A/D converters, LAN, USB, and RS232) allows connection to virtually any chromatograph.
We also represent SEDERE as the leading manufacturer of Low-Temperature Evaporative Light-Scattering Detectors (LT-ELSD) for HPLC, U-HPLC, HTLC, µ-HPLC, GPC, Preparative HPLC, Flash Chromatography, Counter Current Chromatography and SFC.These detectors range from entry-level unit to computer controlled systems for automated analyses thanks to several drivers.
Evaporative Light-Scattering Detectors provide a Universal detection mode for Liquid Chromatography and Supercritical Fluid Chromatography. It does not depend on the presence of chromophore groups on the compound and is therefore an extremely useful technique to get the complete picture of complex samples.
Typical applications include Carbohydrates, Lipids, Surfactants, Polymers but also Pharmaceutical High Throughput Screening and small molecules such as Amino Acids (without any derivation step) or Inorganic Ions (without the need of any additional post-column device). SEDERE LT-ELSDs are commonly used in Industrial, Governmental and University research and control laboratories.